Long story. If you can;t tune the exhuast system to the proper resonant frequency they hurt power more then help and most cars don't have enough wheel base to get the tunning ranges we need. Now the single chambers are easier to work with but who want to listen to those things in a street car ?
My issue is that those mufflers are very hit and miss. Sometimes they work and the world is good. Other time with a small ci motor with a long camshaft and a good amount of overlap they kill the motor.Its also a safe bet a through flow muffler will make power.
All this aside properly configured flowmaster 2-3 chamber mufflers in a properly attenuated exhuast system can actually make more power then a straight through design. You just not likely to see it on a wild card combo like the on in this thread.